杨涛

时间:2020-10-12来源:必赢国际437官方点击:895



杨涛 教授 博士生导师


邮箱:tyang0920@suda.edu.cn

通讯地址:苏州市工业园区仁爱路199号苏州大学云轩楼2213西


个人简历

杨涛,苏州大学特聘教授、博导。2018年于苏州大学获得药剂学博士学位,随后前往Innovation Center of Nanomedicine从事博士后研究,合作导师为美国科学院外籍院士、ACS Nano副主编、纳米医药先驱Kataoka教授。杨涛博士于202112月加入苏州大学药学院,主要从事智能化药物递送、免疫创新制剂的研发,作为通讯作者/第一作者(含共同)在领域内高水平期刊Nat Biomed EngAdv MaterACS NanoBiomaterialsJ Controlled Release等发表影响因子大于10SCI论文12篇,其中ESI高被引论文3篇;作为主持人承担了国家自然科学基金委、日本学术振兴会、江苏省双创计划、姑苏创新创业领军人才等多项科研及人才项目申请发明专利9项,包括3项国际专利和已授权专利2项。受邀担任Frontier In Oncology杂志的评审编辑(Review Editor)。


主要研究方向:

1.生物医用高分子药物载体

2.肿瘤可视化治疗

3.生物医学工程

4.纳米医药及其创新制剂的研发


在研项目:

1.姑苏创新创业领军人才青年项目、2022.07-2025.06、在研、主持。

2.日本学术振兴会青年项目2021.04~2023.03、在研、主持。

3.国家自然科学基金青年科学基金项目、2021.01~2023.12、在研、主持。


代表性论文

1.Li, T.#; Tan, S.#; Li, M.; Luo, J.; Zhang, Y.; Jiang, Z.*; Deng, Y.; Han, L.; Ke, H.; Shen, J.; Tang, Y.; Liu, F.; Chen, H.*; Yang, T.*. Holographically Activatable Nanoprobe via Glutathione/Albumin-Mediated Exponential Signal Amplification for High-Contrast Tumor Imaging. Adv. Mater. 2023, 2209603.

2.Luo, J.#; Miao, Z.#; Huang, X.; Yang, Y.; Liu, M.; Shen, G.*; Yang, T.*. Translational Albumin Nanocarrier Caging Photosensitizer for Efficient Cancer Photodynamic Therapy. Front. Bioeng. Biotechnol. 2023, 11, 1132591.

3.Zhai, Y.#; Liu, M.#; Yang, T.#; Luo, J.; Wei, C.*; Shen, J.*; Song, X.; Ke, H.; Sun, P.; Guo, M.; Deng, Y.*; Chen, H.* Self-Activated Arsenic Manganite Nanohybrids for Visible and Synergistic Thermo/Immuno-Arsenotherapy. J. Control Release2022, 350,761-776.

4.Yang, T.; Mochida, Y.; Liu, X.; Zhou, H.; Xie, J.; Anraku, Y.; Kinoh, H.; Cabral, H.*; Kataoka, K.* Conjugation of Glucosylated Polymer Chains to Checkpoint-Blockade Antibodies Augment Their Efficacy and Specificity for Glioblastoma. Nat. Biomed. Eng. 2021, 5,1274.

5.He, M.#;Yang, T.#; Wang, Y.; Wang, M.; Chen, X.; Ding, D.*; Zheng, Y.*; Chen, H.* Immune Checkpoint Inhibitor-Based Strategies for Synergistic Cancer Therapy. Adv. Healthcare Mater. 2021, 10, 2002104.

6.Iqbal, H.#; Yang, T.#; Li, T.; Zhang, M.; Ke, H.; Ding, D.; Deng, Y.*; Chen, H.* Serum Protein-Based Nanoparticles for Cancer Diagnosis and Treatment. J. Control Release 2020, 329, 997. ESI高被引论文

7.Tang, Y.#; Yang, T.#; Wang, Q.; Lv, X.; Song, X.; Ke, H.; Guo, Z.; Huang, X.; Hu, J.; Li, Z.; Yang, P.*; Yang, X.*; Chen, H.* Albumin-Coordinated Assembly of Clearable Platinum Nanodots for Photo-Induced Cancer Theranostics. Biomaterials,2018, 154, 248.

8.Zhou, L.#; Yang, T.#; Wang, J.#; Wang, Q.; Lv, X.; Ke, H.; Guo, Z.; Shen, J.; Yong, W.*; Xing, C.*; Chen, H.* Size-Tunable Gd2O3@Albumin Nanoparticles Conjugating Chlorin e6 for Magnetic Resonance Imaging-Guided Photo-Induced Therapy. Theranostics,2017, 7, 764.

9.Yang, T.; Liu, L.; Deng, Y.; Guo, Z.; Zhang, G.; Ge, Z.*; Ke, H.*; Chen, H.* Ultrastable Near-Infrared Conjugated-Polymer Nanoparticles for Dually Photoactive Tumor Inhibition. Adv. Mater.2017, 29, 1700487.

10.Yang, T.#; Tang, Y.#; Liu, L.; Lv, X.; Wang, Q.; Ke, H.; Deng, Y.; Yang, H.; Yang, X.; Liu, G.; Zhao, Y.; Chen, H.* Size-Dependent Ag2S Nanodots for Second Near-Infrared Fluorescence/Photoacoustics Imaging and Simultaneous Photothermal Therapy. ACS Nano2017, 11, 1848. ESI高被引论文

11.Yang, T.#; Ke, H.#; Wang, Q.#; Tang, Y.; Deng, Y.*; Yang, H.; Yang, X.; Yang, P.; Ling, D.; Chen, C.; Zhao, Y.; Wu, H.*; Chen, H.* Bifunctional Tellurium Nanodots for Photo-Induced Synergistic Cancer Therapy. ACS Nano2017, 11, 10012.

12.Yang, T.#; Wang, Y.#; Ke, H.; Wang, Q.; Lv, X.; Wu, H.; Tang, Y.; Yang, X.; Chen, C.; Zhao, Y.; Chen, H.* Protein-Nanoreactor-Assisted Synthesis of Semiconductor Nanocrystals for Efficient Cancer Theranostics. Adv. Mater.2016, 28, 5923.

13.Wang, Y.#; Yang, T.#; Ke, H.#; Zhu, A.; Wang, Y.; Wang, J.; Shen, J.; Liu, G.; Chen, C.; Zhao, Y.; Chen, H.* Smart Albumin-Biomineralized Nanocomposites for Multimodal Imaging and Photothermal Tumor Ablation. Adv. Mater.2015, 27, 3874. ESI高被引论文


代表性专利:

1.一种诊疗一体化锰氧化物蛋白纳米粒及其制备方法与应用, ZL202211585598.6

2.THERANOSTIC MANGANESE OXIDE-BASED PROTEIN NANOPARTICLE, PREPARATION METHOD THEREFOR AND USE THEREOF, PCT/CN2022/138242

3.ANTIBODY HAVING REDUCED BINDING AFFINITY FOR ANTIGEN, WO2022/239720A1

4.具有近红外光热效应的铜基人血白蛋白纳米复合物及其制备方法和应用,ZL201510566206.5

5.具有近红外光热效应和多模态成像功能的超小蛋白复合纳米粒及其制备方法和应用,ZL201710829251.4


荣誉奖励:

1.2022年,姑苏创新创业领军人才(青年)

2.2022年,江苏省“双创博士”


招生信息:

本课题组现招收或联合培养有志从事科研工作的硕、博士研究生,博士后,提供有竞争力的待遇,有意者请发简历至tyang0920@suda.edu.cn。并欢迎感兴趣的高年级本科生到课题组实习。欢迎具有药学、化学、材料、或生物学背景的同学报考。